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WHO escalates Ebola outbreak risk assessment
The World Health Organization (WHO) has elevated the public health risk from the Ebola outbreak in the Democratic Republic of Congo (DRC) to "very high" at the national level, while maintaining a "high" risk for the broader African region and a "low" global threat.
Outbreak details and fatalities
The current outbreak, centered in the DRC, involves the rare Bundibugyo strain of Ebola, which has no proven vaccine and a fatality rate of approximately 33%. As of the latest update, authorities have reported 177 suspected deaths and 750 suspected cases. WHO Director-General Dr. Tedros Adhanom Ghebreyesus confirmed 82 laboratory-confirmed cases and seven deaths in a Friday briefing in Geneva.
Vaccine development efforts
Scientists at the University of Oxford are advancing a new Ebola vaccine, leveraging the same technology used for the AstraZeneca COVID-19 vaccine. Animal testing is already underway, with clinical trials expected to begin within two to three months. However, efficacy remains uncertain until further research is completed.
The Serum Institute of India is prepared to mass-produce the vaccine once Oxford supplies medical-grade material. Separately, an experimental Bundibugyo-specific vaccine is in development, though it may take six to nine months before doses are ready for testing. WHO research adviser Dr. Vasee Moorthy called this vaccine "the most promising" option, comparing it to the existing Ervebo vaccine for the Zaire Ebola strain.
Regional spread and security challenges
Neighboring Uganda has reported two confirmed Bundibugyo cases and one death, both linked to travelers from the DRC. The WHO declared the outbreak a Public Health Emergency of International Concern on Sunday but emphasized it does not yet meet pandemic criteria.
Violence and instability in the conflict-ridden region are hampering response efforts. Some cases have emerged in rebel-held areas, complicating containment. Dr. Tedros stressed the need to build trust with local communities to curb transmission.
Community fear and unrest
Distrust and fear have sparked violent incidents, including an attack on Rwampara General Hospital in Ituri province. Relatives of a deceased patient set fire to the facility after health workers refused to release the body due to contamination risks. Police intervened with warning shots to disperse the crowd, and military protection was deployed for medical staff.
"They started throwing projectiles at the hospital. They even set fire to tents that were being used as isolation wards."
Luc Malembe Malembe, local politician
Residents expressed growing anxiety over the outbreak's rapid progression. A taxi driver in Rwampara told the BBC, "Ebola has tortured us. I am scared because people are dying very fast... we are really afraid." Another resident, Fred Kiza, acknowledged the fear as a natural response to such a deadly disease.
Transmission and containment
Ebola spreads through contact with infected animals-typically fruit bats-or through handling contaminated bushmeat. The Bundibugyo strain's rarity limits available medical tools, heightening the urgency for vaccine development and community engagement. Safe burial practices for victims, whose bodies remain highly infectious, are critical to preventing further spread.